Article
Molecular genotyping of fetal platelet antigens with uncultured amniocytes.
American journal of obstetrics and gynecology - 1 Oct 1995
Khouzami A N, Kickler T S, Bray P F, Callan N A, Sciscione A C, Shumway J B, Blakemore K J
Abstract excerpt
OBJECTIVE: Amino acid substitutions in platelet membrane glycoproteins result in alloantigens implicated in neonatal alloimmune thrombocytopenia. We report the use of the reverse dot blot technique to genotype the five major fetal platelet alloantigens from amniotic fluid cells. STUDY DESIGN: We...
Topics
- Adult
- Alleles
- Amniotic Fluid
- Antigens, Human Platelet
- Blood Platelets
- Female
- Fetal Blood
- Fetal Diseases
- Genotype
- Humans
- Molecular Probe Techniques
- Polymerase Chain Reaction
- Pregnancy
- Prenatal Diagnosis
- Thrombocytopenia
