Article
Unusual forms of insulin resistance.
Annual review of medicine - 1 Jan 1991
Taylor S I, Accili D, Cama A, Imano E, Kadowaki H, Kadowaki T
Abstract excerpt
Insulin resistance is an important feature in the pathogenesis of non-insulin-dependent diabetes mellitus. Some rare patients have syndromes associated with a severe form of insulin resistance, usually involving acanthosis nigricans and, in premenopausal females, hyperandrogenism. This review discusses two of the causes of insulin resistance: mutations in the insulin receptor gene and autoantibodies directed...
Topics
- Acanthosis Nigricans
- Blood Glucose
- Diabetes Mellitus, Type 2
- Humans
- Insulin Resistance
- Mutation
- Receptor, Insulin
- Syndrome
- Virilism