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Article

Insulin resistance in polycystic ovary syndrome: treating a phenotype without a genotype.

Molecular and cellular endocrinology - 25 Oct 1998

Legro R S

Abstract excerpt

PCOS women are uniquely insulin resistant. The underlying genetic defect in insulin action is unknown. Obesity aggravates the underlying predisposition to insulin resistance. Diagnostic criteria which focus on menstrual irregularity are more likely to identify insulin resistant women. About 40% of PCOS women display glucose intolerance (either impaired glucose tolerance or type 2 diabetes) in response to an oral...

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Identifiers

PMID: 9922106
DOI: 10.1016/s0303-7207(98)00176-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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