Insulin resistance in polycystic ovary syndrome: treating a phenotype without a genotype.

doi:10.1016/s0303-7207(98)00176-2

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Article

Insulin resistance in polycystic ovary syndrome: treating a phenotype without a genotype.

Molecular and cellular endocrinology - 25 Oct 1998

Legro R S

Abstract excerpt

PCOS women are uniquely insulin resistant. The underlying genetic defect in insulin action is unknown. Obesity aggravates the underlying predisposition to insulin resistance. Diagnostic criteria which focus on menstrual irregularity are more likely to identify insulin resistant women. About 40% o...

Topics

Female
Glucose Intolerance
Humans
Hypoglycemic Agents
Insulin Resistance
Phenotype
Polycystic Ovary Syndrome
Prevalence
Weight Loss

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