Article
Identification of a microsatellite instability phenotype in meningiomas.
Cancer research - 15 Dec 1994
Pykett M J, Murphy M, Harnish P R, George D L
Abstract excerpt
To better understand the molecular mechanisms responsible for meningioma tumorigenesis we previously utilized subtractive hybridization protocols to identify genes the expression or structure of which is altered in these common brain tumors. Here we show that a CA dinucleotide repeat element present in one complementary DNA isolated by this approach has undergone a contraction in size in a meningioma cell line....
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