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Article

Characterization and comparison of genomic profiles between primary cancer cell lines and parent atypical meningioma tumors

28 Jul 2020

Abstract excerpt

BACKGROUND: Meningiomas are the second most common primary tumors of the central nervous system. However, there is a paucity of data on meningioma biology due to the lack of suitable preclinical in vitro and in vivo models. In this study, we report the establishment and characterization of patient-derived, spontaneously immortalized cancer cell lines derived from World Health Organization (WHO) grade I and...

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PMID: 32742192
DOI: 10.1186/s12935-020-01438-x

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