Article
Determination of the enantiomers of mianserin, desmethylmianserin, and 8-hydroxymianserin in the plasma and urine of mianserin-treated patients.
Chirality - 1 Jan 1994
Eap C B, Powell K, Campus-Souche D, Monney C, Baettig D, Taeschner W, Baumann P
Abstract excerpt
An HPLC method is presented which allows the measurement in the same run of the enantiomers of mianserin, desmethylmianserin, and 8-hydroxymianserin in plasma and urine of mianserin-treated patients. Limits of quantitation for the (S)- and (R)-enantiomers of mianserin and desmethylmianserin were...
Topics
- Adult
- Aged
- Aged, 80 and over
- Chromatography, High Pressure Liquid
- Female
- Genotype
- Humans
- Male
- Mianserin
- Middle Aged
- Polymerase Chain Reaction
- Stereoisomerism
