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Article

Multicenter study on the clinical effectiveness, pharmacokinetics, and pharmacogenetics of mirtazapine in depression.

Journal of clinical psychopharmacology - 1 Oct 2012

Jaquenoud Sirot Eveline, Harenberg Sabine, Vandel Pierre, Lima Carlos A Mendonça, Perrenoud Patrick, Kemmerling Klaus, Zullino Daniele F, Hilleret Henriette, Crettol Séverine, Jonzier-Perey Michèle, Golay Kerry Powell, Brocard Muriel, Eap Chin B, Baumann Pierre

Abstract excerpt

Pharmacogenetic tests and therapeutic drug monitoring may considerably improve the pharmacotherapy of depression. The aim of this study was to evaluate the relationship between the efficacy of mirtazapine (MIR) and the steady-state plasma concentrations of its enantiomers and metabolites in moderately to severely depressed patients, taking their pharmacogenetic status into account. Inpatients and outpatients (n =...

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Share to Antidepressive Agents, Tricyclic
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22926595
DOI: 10.1097/JCP.0b013e3182664d98

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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