Analysis of adenomatous polyposis coli gene in thyroid tumours.

doi:10.1038/bjc.1994.452

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Article

Analysis of adenomatous polyposis coli gene in thyroid tumours.

British journal of cancer - 1 Dec 1994

Colletta G, Sciacchitano S, Palmirotta R, Ranieri A, Zanella E, Cama A, Mariani Costantini R, Battista P, Pontecorvi A

Abstract excerpt

Familial adenomatous polyposis (FAP) is known to be associated with neoplasia of various tissues, including thyroid carcinoma. Germline mutations of the tumour-suppressor gene APC, responsible for the predisposition to FAP, may therefore be involved in the pathogenesis of these tumours. In this r...

Topics

Adenomatous Polyposis Coli
Adult
Female
Genes, APC
Humans
Male
Middle Aged
Mutation
Polymorphism, Single-Stranded Conformational
Thyroid Neoplasms

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