Germline mutations of the APC gene in patients with familial adenomatous polyposis-associated thyroid carcinoma: results from a European cooperative study.

doi:10.1210/jcem.85.1.6254

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Article

Germline mutations of the APC gene in patients with familial adenomatous polyposis-associated thyroid carcinoma: results from a European cooperative study.

The Journal of clinical endocrinology and metabolism - 1 Jan 2000

Cetta F, Montalto G, Gori M, Curia M C, Cama A, Olschwang S

Abstract excerpt

Papillary thyroid carcinoma (PTC) is one extracolonic manifestation affecting about 1-2% of patients with familial adenomatous polyposis (FAP). Ninety-seven patients with FAP-associated PTC have previously been reported, including 6 pairs of siblings. During a European collaborative study, 15 patients with FAP-associated PTC were collected. All 15 patients were females. The mean age at thyroidectomy was 24.9 yr...

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PMID: 10634400
DOI: 10.1210/jcem.85.1.6254

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