Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Escherichia coli single-stranded DNA-binding protein: multiple DNA-binding modes and cooperativities.

Annual review of biochemistry - 1 Jan 1994

Lohman T M, Ferrari M E

Abstract excerpt

There are now several well-documented SSBs from both prokaryotes and eukaryotes that function in replication, recombination, and repair; however, no "consensus" view of their interactions with ssDNA has emerged. Although these proteins all bind preferentially and with high affinity to ssDNA, their modes of binding to ssDNA in vitro, including whether they bind with cooperativity, often differ dramatically. This...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Allosteric Regulation
Share to Bacterial Proteins
Share to DNA-Binding Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Escherichia coli

Share to Mutation

Share to Oligodeoxyribonucleotides

Share to Osmolar Concentration

Share to Structure-Activity Relationship

Source

Identifiers

PMID: 7979247
DOI: 10.1146/annurev.bi.63.070194.002523

Genes

SSB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Escherichia coli single-stranded DNA-binding protein: multiple DNA-binding modes and cooperativities.PMID 7979247Read ↗

Monomers of the Escherichia coli SSB-1 mutant protein bind single-stranded DNA.Semantic proximity Read ↗

Multiprotein E. coli SSB-ssDNA complex shows both stable binding and rapid dissociation due to interprotein interactions.Semantic proximity Read ↗

Single-strand DNA-binding protein suppresses illegitimate recombination in Escherichia coli, acting in synergy with RecQ helicase.Semantic proximity Read ↗

The human mitochondrial single-stranded DNA-binding protein displays distinct kinetics and thermodynamics of DNA binding and exchange.Semantic proximity Read ↗

Both OB folds of single-stranded DNA-binding protein are essential for its ssDNA binding activity in Deinococcus radiodurans.Semantic proximity Read ↗

Characterization of a single-stranded DNA-binding protein from Klebsiella pneumoniae: mutation at either Arg73 or Ser76 causes a less cooperative complex on DNA.Semantic proximity Read ↗

Monomer-tetramer equilibrium of the Escherichia coli ssb-1 mutant single strand binding protein.Semantic proximity Read ↗

Role of the single-stranded DNA-binding protein SsbB in pneumococcal transformation: maintenance of a reservoir for genetic plasticity.Semantic proximity Read ↗

Crowding on DNA modulates SSB protein binding mode kineticsSemantic proximity Read ↗

Escherichia coli single-stranded DNA-binding protein mediates template recycling during transcription by bacteriophage N4 virion RNA polymerase.Semantic proximity Read ↗

The Impact of Single-Stranded DNA-Binding Protein SSB and Putative SSB-Interacting Proteins on Genome Integrity in the Thermophilic Crenarchaeon Sulfolobus acidocaldarius.Semantic proximity Read ↗

Mutations in the N-terminal cooperativity domain of gene 32 protein alter properties of the T4 DNA replication and recombination systems.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.