Article
Monomer-tetramer equilibrium of the Escherichia coli ssb-1 mutant single strand binding protein.
The Journal of biological chemistry - 25 Jan 1991
Bujalowski W, Lohman T M
Abstract excerpt
The Escherichia coli single strand binding (SSB) protein is an essential protein required for DNA replication and involved in recombination and a number of repair processes. It is a stable homotetramer in solution; however the ssb-1 mutation (His-55 to Tyr) destabilizes the tetramer with respect to monomers and this defect seems to explain the observed phenotype (Williams, K. R., Murphy, J. B., and Chase, J. W....
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