Developmental effects of an environmental antiandrogen: the fungicide vinclozolin alters sex differentiation of the male rat.

Abstract excerpt

In humans and rodents, exposure to hormonally active chemicals during sex differentiation can produce a wide range of abnormal sexual phenotypes including masculinized and defeminized females and feminized and demasculinized males. Although numerous "environmental estrogens," including pesticides, toxic substances (PCBs), and plant and fungal estrogens, have been shown to alter mammalian sex differentiation,...

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