Article
Latent effects of pesticides and toxic substances on sexual differentiation of rodents.
Toxicology and industrial health - 1 Jan 2000
Gray L E, Kelce W R
Abstract excerpt
In humans and rodents, exposure to hormonally active chemicals during sex differentiation can produce morphological pseudohermaphrodism (Schardein, 1993; Gray, 1992). For example, hormonally active drugs like DES (estrogenic), Danazol (androgenic), and progestins cause urogenital malformations in...
Topics
- Abnormalities, Drug-Induced
- Androgen Antagonists
- Animals
- Cricetinae
- Embryonic and Fetal Development
- Female
- Germ Cells
- Gestational Age
- Male
- Phenotype
- Polychlorinated Dibenzodioxins
- Pregnancy
- Prenatal Exposure Delayed Effects
- Rats
- Reproduction
- Sex Differentiation
- Sperm Count