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Article

Carnitine suppression of position-effect variegation in Drosophila melanogaster.

Molecular & general genetics : MGG - 28 Sept 1994

Fanti L, Berloco M, Pimpinelli S

Abstract excerpt

Carnitine is a well-known naturally occurring compound, very similar to butyrate, with an essential role in intermediary metabolism mainly at the mitochondrial level. Since butyrate inhibits the enzyme histone deacetylase and is capable of suppressing position-effect variegation in Drosophila melanogaster, we tested a further possible function of carnitine in the nucleus, using an assay for the suppression of...

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PMID: 7969027
DOI: 10.1007/BF00282748

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