Article
Risk of pregnancy-related venous thrombosis in carriers of severe inherited thrombophilia.
Thrombosis and haemostasis - 1 Sept 2001
Martinelli I, Legnani C, Bucciarelli P, Grandone E, De Stefano V, Mannucci P M
Abstract excerpt
Homozygous carriers of factor V Leiden have an approximately 80-fold increased risk of venous thrombosis. Also double heterozygous carriers of both the factor V Leiden and the prothrombin gene mutations are at high thrombotic risk. The magnitude of the risk of venous thrombosis in pregnant women with the two severe thrombophilic conditions has not been estimated so far. We performed a multicenter retrospective...
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