Article
Are factor V Leiden carriers who use oral contraceptives at extreme risk for venous thromboembolism?
The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception - 1 Jun 2000
Spannagl M, Heinemann L A, Schramm W
Abstract excerpt
BACKGROUND: Major concern was raised by an earlier study regarding oral contraceptive use in women with the factor V Leiden mutation. A more than 30-fold increase in relative risk for venous thromboembolism was reported; for homozygotes, the relative risk was as much as 100-fold or more. OBJECTIVE: To replicate the reported risk estimates with a new population-based case-control study. METHODS: Eighty women with...
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