Position-based sequence weights.

Abstract excerpt

Sequence weighting methods have been used to reduce redundancy and emphasize diversity in multiple sequence alignment and searching applications. Each of these methods is based on a notion of distance between a sequence and an ancestral or generalized sequence. We describe a different approach, which bases weights on the diversity observed at each position in the alignment, rather than on a sequence distance...

Topics

• Amino Acid Sequence
• Base Sequence
• Computer Simulation
• Databases, Factual
• Genetic Variation
• Molecular Sequence Data
• Sequence Alignment