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Article

T cell cross-reactivity between coxsackievirus and glutamate decarboxylase is associated with a murine diabetes susceptibility allele.

The Journal of experimental medicine - 1 Nov 1994

Tian J, Lehmann P V, Kaufman D L

Abstract excerpt

Limited regions of amino acid sequence similarity frequently occur between microbial antigens and host proteins. It has been widely anticipated that during infection such sequence similarities could induce cross-reactive T cell responses, thereby initiating T cell-mediated autoimmune disease. However, the nature of major histocompatibility complex (MHC)-restricted antigen presentation confers a number of...

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Identifiers

PMID: 7964474
DOI: 10.1084/jem.180.5.1979
PMCID: PMC2191714

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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T cell cross-reactivity between coxsackievirus and glutamate decarboxylase is associated with a murine diabetes susceptibility allele.PMID 7964474Read ↗

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Cellular immunity to a determinant common to glutamate decarboxylase and coxsackie virus in insulin-dependent diabetes.Semantic proximity Read ↗

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Similarities between bacterial GAD and human GAD65: Implications in gut mediated autoimmune type 1 diabetesSemantic proximity Read ↗

Identification of peptides from autoantigens GAD65 and IA-2 that bind to HLA class II molecules predisposing to or protecting from type 1 diabetes.Semantic proximity Read ↗

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