Article
Genotypic and phenotypic analysis of human immunodeficiency virus type 1 isolates from patients on prolonged stavudine therapy.
The Journal of infectious diseases - 1 Nov 1994
Lin P F, Samanta H, Rose R E, Patick A K, Trimble J, Bechtold C M, Revie D R, Khan N C, Federici M E, Li H
Abstract excerpt
Development of stavudine resistance was studied using human immunodeficiency virus type 1 isolates from 13 patients treated with stavudine for 18-22 months. Drug sensitivity testing on 11 of these pre- and posttherapy isolates identified only 2 posttreatment isolates with decreased stavudine sens...
Topics
- Acquired Immunodeficiency Syndrome
- Base Sequence
- Drug Resistance
- Genotype
- HIV-1
- Humans
- Molecular Sequence Data
- Phenotype
- Stavudine
- Zidovudine
