Article
Stavudine resistance: an update on susceptibility following prolonged therapy.
Antiviral therapy - 1 Jan 1999
Lin P F, González C J, Griffith B, Friedland G, Calvez V, Ferchal F, Schinazi R F, Shepp D H, Ashraf A B, Wainberg M A, Soriano V, Mellors J W, Colonno R J
Abstract excerpt
The current report summarizes the available published and unpublished data from several investigators on resistance in clinical isolates following prolonged stavudine therapy. Results suggest that stavudine resistance is both modest in degree and infrequent in appearance. Phenotypic evaluation of 61 patients on stavudine therapy showed only modest changes in drug sensitivity following up to 29 months of...
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