Article
Molecular analysis of HLA DRB1 and DQB1 polymorphism in Italian melanoma patients.
Journal of immunotherapy (Hagerstown, Md. : 1997) - 1 Nov 1998
Lombardi M L, Mercuro O, Pirozzi G, Ionna F, Lombari V, Mozzillo N, Manzo C
Abstract excerpt
Several studies have reported association between a variety of malignancies and human leukocyte antigens (HLA) genes. However, conflicting data have been reported on HLA association and melanoma. We report here serologic and molecular analysis by polymerase chain reaction sequence-specific primer...
Topics
- Alleles
- Antigens, Neoplasm
- Biomarkers, Tumor
- Case-Control Studies
- Gene Frequency
- HLA-DQ Antigens
- HLA-DQ beta-Chains
- HLA-DR Antigens
- HLA-DRB1 Chains
- Humans
- Italy
- Melanoma
- Polymorphism, Genetic