Effects of fecal microorganisms and their chloroform-resistant variants derived from mice, rats, and humans on immunological and physiological characteristics of the intestines of ex-germfree mice.

doi:10.1128/iai.62.12.5442-5446.1994

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Article

Effects of fecal microorganisms and their chloroform-resistant variants derived from mice, rats, and humans on immunological and physiological characteristics of the intestines of ex-germfree mice.

Infection and immunity - 1 Dec 1994

Okada Y, Setoyama H, Matsumoto S, Imaoka A, Nanno M, Kawaguchi M, Umesaki Y

Abstract excerpt

In order to elucidate the nature of intestinal flora affecting the immunological and physiological parameters of the intestine, we produced several kinds of ex-germfree mice associated with fecal organisms and their chloroform-resistant variants derived from mice, rats, and humans. The phenotypes of intraepithelial lymphocytes were changed to those in conventional mice, particularly the increased positive...

Topics

Animals
Carboxylic Acids
Cecum
Chloroform
Drug Resistance, Microbial
Feces
Female
Genetic Variation
Germ-Free Life
Glycolipids
Histocompatibility Antigens Class II

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Intestinal Mucosa

Intestines

Male

Mice

Mice, Inbred Strains

Rats

Source

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Identifiers

PMID: 7960124
DOI: 10.1128/iai.62.12.5442-5446.1994
PMCID: PMC303286

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7960124-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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