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Altering Host Resistance to Infections through Microbial Transplantation

28 Oct 2011

Abstract excerpt

Host resistance to bacterial infections is thought to be dictated by host genetic factors. Infections by the natural murine enteric pathogen Citrobacter rodentium (used as a model of human enteropathogenic and enterohaemorrhagic E. coli infections) vary between mice strains, from mild self-resolving colonization in NIH Swiss mice to lethality in C3H/HeJ mice. However, no clear genetic component had been shown to...

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PMID: 22046427
DOI: 10.1371/journal.pone.0026988

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