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Article

Detection of beta-thalassaemia mutations in eastern Indian population by polymerase chain reaction.

The Indian journal of medical research - 1 Sept 1994

Ghosh Dastidar D, Dutta R N, Gupta P, Old J M

Abstract excerpt

We report here the application of a non-radioactive amplification refractory mutation system (ARMS) for the direct detection of beta-thalassaemia using polymerase chain reaction. Seven beta-thalassaemia mutations accounting for 89 per cent (71 of 80) of the alleles in eastern Indian population have been identified and majority (67.5%) were due to IVS-1 nt 5 (G-C) mutation. Interestingly, 9 cases did not reveal...

Topics

Alleles
DNA Primers
Humans
India
Mutation
Polymerase Chain Reaction
beta-Thalassemia

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7959966

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7959966-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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