Article
Beta-thalassemia mutations in western India.
Indian journal of pediatrics - 1 Jun 2008
Sheth J J, Sheth F J, Pandya Pooja, Priya Rashi, Davla Sejal, Thakur Chitra, Flavin Vaz
Abstract excerpt
OBJECTIVE: To study occurrence of common mutations in the population of Gujarat and the most prevalent mutation in certain high-risk communities. METHODS: The mutation screening was carried out using ARMS-PCR in children with beta thalassemia. RESULTS: Population screening has identified certain communities like Sindhis, Lohana, Rajputs, and SC/ST/OBC to be at higher risk as compared to others. The most common...
Topics
- Alleles
- DNA Mutational Analysis
- Ethnicity
- Fetus
- Frameshift Mutation
- Genetic Testing
- Humans
- India
- Point Mutation
- Polymerase Chain Reaction
- Prenatal Diagnosis
- Prevalence