Experience with multiplex ARMS (MARMS)-PCR for the detection of common β-thalassemia mutations in India.

Abstract excerpt

Beta (β) Thalassemia is a common globin gene disorder in India. Although about 65 different mutations are known in the multiethnic populations of India, the group of 9 'core mutations', i.e. IVSI,5 (G > C){HBB:c.925G > C}, 619 base pair deletion(bp del){NG_000007.3:g.71609_72227del619}, FS8/9 (G)...

Topics

• DNA
• DNA Mutational Analysis
• Genetic Testing
• Humans
• India
• Multiplex Polymerase Chain Reaction
• Mutation
• beta-Thalassemia