Quantitative trait locus for reading disability on chromosome 6.

doi:10.1126/science.7939663

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Article

Quantitative trait locus for reading disability on chromosome 6.

Science (New York, N.Y.) - 14 Oct 1994

Cardon L R, Smith S D, Fulker D W, Kimberling W J, Pennington B F, DeFries J C

Abstract excerpt

Interval mapping of data from two independent samples of sib pairs, at least one member of whom was reading disabled, revealed evidence for a quantitative trait locus (QTL) on chromosome 6. Results obtained from analyses of reading performance from 114 sib pairs genotyped for DNA markers localized the QTL to 6p21.3. Analyses of corresponding data from an independent sample of 50 dizygotic twin pairs provided...

Topics

Adolescent
Adult
Alleles
Child
Chromosome Mapping
Chromosomes, Human, Pair 6
Diseases in Twins
Dyslexia
Female
Genetic Linkage
Genetic Markers
HLA Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Major Histocompatibility Complex

Male

Nuclear Family

Regression Analysis

Twins, Dizygotic

Source

Open in PubMed

Identifiers

PMID: 7939663
DOI: 10.1126/science.7939663

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7939663-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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