Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evidence for linkage and association with reading disability on 6p21.3-22.

American journal of human genetics - 1 May 2002

Kaplan D E, Gayán J, Ahn J, Won T-W, Pauls D, Olson R K, DeFries J C, Wood F, Pennington B F, Page G P, Smith S D, Gruen J R

Abstract excerpt

Reading disability (RD), or dyslexia, is a common heterogeneous syndrome with a large genetic component. Several studies have consistently found evidence for a quantitative-trait locus (QTL) within the 17 Mb (14.9 cM) that span D6S109 and D6S291 on chromosome 6p21.3-22. To characterize further linkage to the QTL, to define more accurately the location and the effect size, and to identify a peak of association, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Mapping
Share to Chromosomes, Human, Pair 6

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Diseases in Twins

Share to Dyslexia

Share to Genetic Markers

Share to Linkage Disequilibrium

Share to Quantitative Trait, Heritable

Share to Tandem Repeat Sequences

Source

Open in PubMed Open full text

Identifiers

PMID: 11951179
DOI: 10.1086/340449
PMCID: PMC447603

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence for linkage and association with reading disability on 6p21.3-22.PMID 11951179Read ↗

Linkage disequilibrium mapping provides further evidence of a gene for reading disability on chromosome 6p21.3-22.Semantic proximity Read ↗

A 77-kilobase region of chromosome 6p22.2 is associated with dyslexia in families from the United Kingdom and from the United States.Semantic proximity Read ↗

Quantitative trait locus for reading disability on chromosome 6.Semantic proximity Read ↗

A quantitative-trait locus on chromosome 6p influences different aspects of developmental dyslexia.Semantic proximity Read ↗

Association of reading disability on chromosome 6p22 in the Afrikaner population.Semantic proximity Read ↗

Association of attention-deficit/hyperactivity disorder with a candidate region for reading disabilities on chromosome 6p.Semantic proximity Read ↗

Genome-wide scan of reading ability in affected sibling pairs with attention-deficit/hyperactivity disorder: unique and shared genetic effects.Semantic proximity Read ↗

A transcription map of the 6p22.3 reading disability locus identifying candidate genes.Semantic proximity Read ↗

Genome-wide association study of word reading: Overlap with risk genes for neurodevelopmental disorders.Semantic proximity Read ↗

Mapping for dyslexia and related cognitive trait loci provides strong evidence for further risk genes on chromosome 6p21.Semantic proximity Read ↗

In search of the perfect phenotype: an analysis of linkage and association studies of reading and reading-related processes.Semantic proximity Read ↗

Continuing the search for dyslexia genes on 6p.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.