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Article

Hot-spot p53 mutants interact specifically with two cellular proteins during progression of the cell cycle.

Molecular and cellular biology - 1 Oct 1994

Chen Y, Chen P L, Lee W H

Abstract excerpt

Inactivation of both alleles of the p53 gene is commonly found in human cancers. In contrast to mutations of the retinoblastoma gene, certain altered forms of p53 gain growth-promoting functions. To explore the mechanisms underlying this gain of function, we have identified two nuclear proteins, with molecular masses of 42 and 38 kDa, respectively, that are specifically associated with p53 mutated within the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 7935394
DOI: 10.1128/mcb.14.10.6764-6772.1994
PMCID: PMC359207

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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