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Article

Large genomic rearrangements of the unstable region in Streptomyces ambofaciens are associated with major changes in global gene expression.

Molecular microbiology - 1 Nov 1993

Dary A, Kaiser P, Bourget N, Thompson C J, Simonet J M, Decaris B

Abstract excerpt

Global gene expression is dramatically altered by genomic rearrangements in Streptomyces ambofaciens RP181110. Partial genome mapping of two derivatives of strain RP181110 (strains NSA205 and NSA228) revealed rearrangements located in the unstable region of the genome (deletion in strain NSA228; deletion and amplification in strain NSA205). Computerized comparisons of pulse-labelled proteins separated by...

Topics

Bacterial Proteins
Chromosome Mapping
DNA Probes
DNA, Bacterial
Gene Expression Regulation, Bacterial
Gene Rearrangement
Genome, Bacterial
Mutation
Streptomyces

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 7934838
DOI: 10.1111/j.1365-2958.1993.tb00946.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7934838-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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