Article
Kinetics and regulation of pantothenate kinase from Escherichia coli.
The Journal of biological chemistry - 28 Oct 1994
Song W J, Jackowski S
Abstract excerpt
Pantothenate kinase catalyzes the rate-controlling step in coenzyme A (CoA) biosynthesis and is regulated by feedback inhibition by CoA. Pantothenate kinase was purified to homogeneity from Escherichia coli and was shown to exist as a homodimer. Kinetic analysis indicated the presence of two ATP...
Topics
- Adenosine Triphosphate
- Allosteric Regulation
- Amino Acid Sequence
- Base Sequence
- Escherichia coli
- Feedback
- Kinetics
- Molecular Sequence Data
- Mutation
- Pantothenic Acid
- Particle Size
- Phosphotransferases (Alcohol Group Acceptor)
- Protein Conformation
- Recombinant Fusion Proteins
