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Article

Modeling and numerical simulation of biotin carboxylase kinetics: implications for half-sites reactivity.

Journal of theoretical biology - 7 May 2007

de Queiroz Marcio S, Waldrop Grover L

Abstract excerpt

Biotin carboxylase catalyzes the ATP-dependent carboxylation of biotin and is one component of the multienzyme complex acetyl-CoA carboxylase that catalyzes the first committed step in fatty acid synthesis in all organisms. In Escherichia coli, biotin carboxylase exists as a homodimer where each subunit contains a complete active site. In a previous study (Janiyani, K., Bordelon, T., Waldrop, G.L., Cronan Jr.,...

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Identifiers

PMID: 17266990
DOI: 10.1016/j.jtbi.2006.12.025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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