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Article

Converting catabolic ornithine carbamoyltransferase to an anabolic enzyme.

The Journal of biological chemistry - 5 Sept 1990

Baur H, Tricot C, Stalon V, Haas D

Abstract excerpt

Pseudomonas aeruginosa has an anabolic and a catabolic ornithine carbamoyltransferase (OTCase). In vitro, these homologous enzymes catalyze the same reaction (ornithine + carbamoyl phosphate (CP) in equilibrium citrulline + Pi), yet in vivo they function unidirectionally owing to specific kinetic properties. The catabolic OTC-ase cannot promote the anabolic reaction (citrulline formation) in vivo because of a...

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Identifiers

PMID: 2118516

Genes

OTC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Converting catabolic ornithine carbamoyltransferase to an anabolic enzyme.PMID 2118516Read ↗

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