Article
The accumulation of glutamate is necessary for optimal growth of Salmonella typhimurium in media of high osmolality but not induction of the proU operon.
Journal of bacteriology - 1 Oct 1994
Csonka L N, Ikeda T P, Fletcher S A, Kustu S
Abstract excerpt
Synthesis of glutamate can be limited in bacterial strains carrying mutations to loss of function of glutamate synthase (2-oxoglutarate:glutamine aminotransferase) by using low concentrations of NH4+ in the growth medium. By using such gltB/D mutant strains of Salmonella typhimurium, we demonstra...
Topics
- Amino Acid Transport Systems
- Bacterial Proteins
- Betaine
- Carrier Proteins
- Gene Expression Regulation, Bacterial
- Glutamate Synthase
- Glutamates
- Glutamic Acid
- Mutation
- Operon
- Osmotic Pressure
- Proline
- Promoter Regions, Genetic
- Protein Biosynthesis
- Quaternary Ammonium Compounds