Article
Role of glutathione in the response of Escherichia coli to osmotic stress.
Biochemistry. Biokhimiia - 1 Sept 2001
Smirnova G V, Krasnykh T A, Oktyabrsky O N
Abstract excerpt
The growth of Escherichia coli mutants deficient in glutathione synthesis (gshA) and in glutathione reductase (gor) was suppressed in medium of elevated osmolarity. A mutant in gamma-glutamyl transpeptidase (ggt) displayed better ability for osmoadaptation than the parental strain. The unfavorable effect of the gsh mutation on osmoadaptation of growing E. coli cells was more pronounced at low concentrations of K+...
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