Article
Characterization of Bacillus subtilis mutants with carbon source-independent glutamate biosynthesis.
Journal of molecular microbiology and biotechnology - 1 Jan 2007
Commichau Fabian M, Wacker Ingrid, Schleider Jan, Blencke Hans-Matti, Reif Irene, Tripal Philipp, Stülke Jörg
Abstract excerpt
Bacillus subtilis synthesizes glutamate from 2-oxoglutarate and glutamine using the glutamate synthase, encoded by the gltAB operon. Glutamate degradation involves the catabolic glutamate dehydrogenase (GDH) RocG. Expression of both gltAB and rocG is controlled by the carbon and nitrogen sources. In the absence of glucose or other well-metabolizable carbon sources, B. subtilis is unable to grow unless provided...
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