Phenotype variants, malignancy, and additional copies of 6p in retinoblastoma.

doi:10.1016/0165-4608(94)90459-6

Back to search

Article

Phenotype variants, malignancy, and additional copies of 6p in retinoblastoma.

Cancer genetics and cytogenetics - 1 Sept 1994

Cano J, Oliveros O, Yunis E

Abstract excerpt

Thirty-four of 51 (67%) primary retinoblastomas were analyzed cytogenetically to characterize the type of events that result in additional copies of the short arm of chromosome 6 and their implications in this malignancy. Of the 34 tumors studied, additional copies of 6p were found in 14 (41%). T...

Topics

Chromosomes, Human, Pair 6
Eye Neoplasms
Gene Amplification
Humans
Karyotyping
Phenotype
Retinoblastoma

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.