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Article

Gain of Chromosome 6p Correlates with Severe Anaplasia, Cellular Hyperchromasia, and Extraocular Spread of Retinoblastoma

11 Dec 2021

Abstract excerpt

Purpose Gain of chromosome 6p has been associated with poor ocular survival in retinoblastoma and histopathologic grading of anaplasia with increased risk of metastatic spread and death. This study examined the correlation between these factors and other chromosomal abnormalities as well as results of whole genome sequencing, digital morphometry, and progression-free survival. Design Retrospective cohort study...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36246172
DOI: 10.1016/j.xops.2021.100089

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