DNA repair. DNA surveillance defect in cancer cells.

doi:10.1016/s0960-9822(00)00056-7

Back to search

Article

DNA repair. DNA surveillance defect in cancer cells.

Current biology : CB - 1 Mar 1994

Lindahl T

Abstract excerpt

A defect in a protein involved in DNA-mismatch correction accounts for a common type of hereditary colon cancer, adding to the evidence that DNA repair is central to counteracting the transformation of human cells.

Topics

Adenosine Triphosphatases
Bacterial Proteins
Cell Transformation, Neoplastic
Colorectal Neoplasms, Hereditary Nonpolyposis
DNA Repair
DNA-Binding Proteins
Escherichia coli
Escherichia coli Proteins
Humans
Models, Biological
MutS DNA Mismatch-Binding Protein
Mutation

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.