Article
Role of carboxy-terminal region in proofreading function of methionyl-tRNA synthetase in Escherichia coli.
Biochemistry - 27 Sept 1994
Gao W, Goldman E, Jakubowski H
Abstract excerpt
The synthetic and editing functions of three forms of Escherichia coli methionyl-tRNA synthetase with different C-terminal sequences have been compared in vivo and in vitro. These forms include a full-length wild-type dimer (MRS676), a truncated monomer (MRS547) believed to be equivalent to the b...
Topics
- Escherichia coli
- Genetic Variation
- Homocysteine
- Methionine-tRNA Ligase
- RNA Editing
- Recombinant Proteins
- Sequence Analysis
- Sequence Deletion
- Structure-Activity Relationship