Article
Analysis of cytotoxic T lymphocyte responses to SIV proteins in SIV-infected macaques using antigen-specific stimulation with recombinant vaccinia and fowl poxviruses.
AIDS research and human retroviruses - 1 May 1994
Kent S J, Stallard V, Corey L, Hu S L, Morton W R, Gritz L, Panicali D L, Greenberg P D
Abstract excerpt
Methods to analyze CD8+ CTL responses to simian immunodeficiency virus (SIV)-encoded proteins are essential to understand lentivirus immunopathogenesis and protective immune responses. Recombinant infectious shuttle vectors are useful for analyzing CTL responses to many viruses, including HIV. Th...
Topics
- Animals
- Antigens, Viral
- Cell Line
- Concanavalin A
- Fowlpox virus
- Fusion Proteins, gag-pol
- Gene Products, env
- Genetic Vectors
- Macaca fascicularis
- Phenotype
- Recombination, Genetic
- Retroviridae Proteins
- Retroviridae Proteins, Oncogenic
- Simian Acquired Immunodeficiency Syndrome