Article
Three epitopic peptides of the simian immunodeficiency virus Nef protein recognized by macaque cytolytic T lymphocytes.
Journal of virology - 1 Feb 1992
Bourgault I, Venet A, Levy J P
Abstract excerpt
In 8 of 12 experimentally infected macaques, the Nef SIVmac 251 protein was recognized by cytolytic T lymphocytes (CTL) and appeared strongly immunogenic. Here, we report experiments which have been performed by using synthetic peptides to precisely determine the epitopes recognized by macaque CT...
Topics
- Amino Acid Sequence
- Animals
- B-Lymphocytes
- Cell Line
- Cell Transformation, Viral
- Cytotoxicity, Immunologic
- Epitopes
- Gene Products, nef
- Kinetics
- Macaca mulatta
- Molecular Sequence Data
- Peptides
- Phenotype
- Recombination, Genetic
- Simian Acquired Immunodeficiency Syndrome
- Simian Immunodeficiency Virus
- T-Lymphocytes, Cytotoxic