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Defined mutants of Proteus mirabilis lacking flagella cause ascending urinary tract infection in mice.

Microbial pathogenesis - 1 Nov 1996

Legnani-Fajardo C, Zunino P, Piccini C, Allen A, Maskell D

Abstract excerpt

A clinical isolate of Proteus mirabilis (Pr 990) and an isogenic non-flagellate allelic replacement mutant (Pr M9) were tested for their ability to cause infection in the ascending mouse model of urinary tract infection. Wild-type Pr 990 differentiates into swarmer cells in brain-heart infusion broth. Pr M9 neither has flagella nor does it apparently differentiate into swarmer cells after subculturing. The...

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Identifiers

PMID: 8938645
DOI: 10.1006/mpat.1996.0070

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Defined mutants of Proteus mirabilis lacking flagella cause ascending urinary tract infection in mice.PMID 8938645Read ↗

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