Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Defined mutants of Proteus mirabilis lacking flagella cause ascending urinary tract infection in mice.

Microbial pathogenesis - 1 Nov 1996

Legnani-Fajardo C, Zunino P, Piccini C, Allen A, Maskell D

Abstract excerpt

A clinical isolate of Proteus mirabilis (Pr 990) and an isogenic non-flagellate allelic replacement mutant (Pr M9) were tested for their ability to cause infection in the ascending mouse model of urinary tract infection. Wild-type Pr 990 differentiates into swarmer cells in brain-heart infusion b...

Topics

Alleles
Animals
Cattle
Chickens
Cloning, Molecular
Disease Models, Animal
Female
Flagella
Flagellin
Guinea Pigs
Horses
Humans
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutagenesis

Phenotype

Proteus Infections

Proteus mirabilis

Sheep

Source

Identifiers

PMID: 8938645
DOI: 10.1006/mpat.1996.0070

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8938645-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Defined mutants of Proteus mirabilis lacking flagella cause ascending urinary tract infection in mice.PMID 8938645Read ↗

The role of swarm cell differentiation and multicellular migration in the uropathogenicity of Proteus mirabilis.Semantic proximity Read ↗

Construction of an MR/P fimbrial mutant of Proteus mirabilis: role in virulence in a mouse model of ascending urinary tract infection.Semantic proximity Read ↗

Proteus mirabilis fimbriae: construction of an isogenic pmfA mutant and analysis of virulence in a CBA mouse model of ascending urinary tract infection.Semantic proximity Read ↗

New aspects of the role of MR/P fimbriae in Proteus mirabilis urinary tract infection.Semantic proximity Read ↗

Swarming and pathogenicity of Proteus mirabilis in the urinary tractSemantic proximity Read ↗

Construction of a flagellum-negative mutant of Proteus mirabilis: effect on internalization by human renal epithelial cells and virulence in a mouse model of ascending urinary tract infection.Semantic proximity Read ↗

Virulence of a Proteus mirabilis ATF isogenic mutant is not impaired in a mouse model of ascending urinary tract infection.Semantic proximity Read ↗

Mannose-resistant Proteus-like fimbriae are produced by most Proteus mirabilis strains infecting the urinary tract, dictate the in vivo localization of bacteria, and contribute to biofilm formation.Semantic proximity Read ↗

Proteus mirabilis isolates of different origins do not show correlation with virulence attributes and can colonize the urinary tract of mice.Semantic proximity Read ↗

Ultrastructure of Proteus mirabilis swarmer cell rafts and role of swarming in catheter-associated urinary tract infection.Semantic proximity Read ↗

Identification of MrpI as the sole recombinase that regulates the phase variation of MR/P fimbria, a bladder colonization factor of uropathogenic Proteus mirabilisSemantic proximity Read ↗

Construction of a urease-negative mutant of Proteus mirabilis: analysis of virulence in a mouse model of ascending urinary tract infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.