Article
DNA variants at the LPL gene locus associate with angiographically defined severity of atherosclerosis and serum lipoprotein levels in a Welsh population.
Arteriosclerosis and thrombosis : a journal of vascular biology - 1 Jul 1994
Mattu R K, Needham E W, Morgan R, Rees A, Hackshaw A K, Stocks J, Elwood P C, Galton D J
Abstract excerpt
Coronary artery disease (CAD) patients (n = 235), comprising minimal (CAD-, n = 124) and severe (CAD+, n = 111) CAD, were recruited on the basis of their angiographic scores. Male control subjects (n = 123) were selected randomly from the Caerphilly Heart Study cohort. Subjects were genotyped for the Ser447-Ter mutation and HindIII/Pvu II restriction fragment length polymorphisms of the lipoprotein lipase gene...
Topics
- Alleles
- Apoproteins
- Base Sequence
- Biomarkers
- Cholesterol
- Coronary Angiography
- Coronary Artery Disease
- DNA
- DNA Mutational Analysis
- DNA Primers