Article
Lipoprotein and hepatic lipase gene variants in coronary atherosclerosis.
Atherosclerosis - 1 Nov 1990
Thorn J A, Chamberlain J C, Alcolado J C, Oka K, Chan L, Stocks J, Galton D J
Abstract excerpt
Lipoprotein lipase is the rate determining enzyme for the removal of triglyceride rich lipoproteins from the blood stream. We examined whether genetic variation at the lipoprotein lipase gene locus is related to the occurrence of premature coronary artery disease. Two restriction fragment length polymorphisms, revealed by the enzymes HindIII and PvuII, demonstrated alleles designated H1 (17.5 kb), H2 (8.7 kb), P1...
Topics
- Alleles
- Coronary Artery Disease
- Genetic Markers
- Genotype
- Humans
- Lipase
- Lipoprotein Lipase
- Liver
- Male
- Middle Aged
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length
