Article
Progress in a genome scan for linkage in schizophrenia in a large Swedish kindred.
American journal of medical genetics - 15 Mar 1994
Barr C L, Kennedy J L, Pakstis A J, Wetterberg L, Sjögren B, Bierut L, Wadelius C, Wahlström J, Martinsson T, Giuffra L
Abstract excerpt
Genetic linkage studies of a kindred from Sweden segregating for schizophrenia have been performed using a genetic model (autosomal dominant, f = 0.72, q = 0.02, phenocopies = 0.001) as described in Kennedy et al., 1988. Analyses of the restriction fragment length polymorphism (RFLP), allele-spec...
Topics
- Alleles
- Finland
- Genes, Dominant
- Genetic Linkage
- Genome, Human
- Humans
- Lod Score
- Models, Genetic
- Oligonucleotide Probes
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length
- Repetitive Sequences, Nucleic Acid
- Restriction Mapping
- Schizophrenia
- Sweden