Article
Strategies for linkage studies in schizophrenia.
Schizophrenia research - 1 Jan 2000
Mellon C D, Byerley W F
Abstract excerpt
Significant advances in linkage studies have occurred the past decade based on the use of polymorphic DNA markers known as restriction fragment length polymorphisms (RFLPs). This approach has led to the chromosomal localization of a number of important genetic diseases, and is being increasingly applied to schizophrenia. We discuss two strategies for performing linkage studies in schizophrenia, one based on...
Topics
- Chromosome Aberrations
- Chromosome Disorders
- Genetic Linkage
- Genetic Markers
- Humans
- Phenotype
- Polymorphism, Restriction Fragment Length
- Schizophrenia
- Schizophrenic Psychology