Article
GAG triplets as splice acceptors of last resort. An unusual form of alternative splicing in prothymosin alpha pre-mRNA.
Journal of molecular biology - 20 Nov 1993
Manrow R E, Berger S L
Abstract excerpt
Prothymosin alpha pre-mRNAs are alternatively spliced as a consequence of adjacent AG acceptor couplets at the intron 2/exon 3 boundary of the only expressed human prothymosin alpha gene. These acceptors are found in a unique sequence motif, GAGGAG, located immediately 3' to a consensus polypyrimidine tract. The frequency with which each acceptor is utilized appears to be invariant in all human cells and tissues...
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