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Article

Clustered alpha-amanitin resistance mutations in mouse.

Molecular & general genetics : MGG - 20 Mar 1995

Bartolomei M S, Corden J L

Abstract excerpt

We report the identification of three new alpha-amanitin resistance mutations in the gene encoding the largest subunit of mouse RNA polymerase II (RPII215). These mutations are clustered in a region of the largest subunit that is important for transcription elongation. This same domain has been identified as the site of alpha-amanitin resistance mutations in both Drosophila and Caenarhabditis elegans. The...

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PMID: 7898449
DOI: 10.1007/BF00290727

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