Clustered alpha-amanitin resistance mutations in mouse.

doi:10.1007/BF00290727

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Article

Clustered alpha-amanitin resistance mutations in mouse.

Molecular & general genetics : MGG - 20 Mar 1995

Bartolomei M S, Corden J L

Abstract excerpt

We report the identification of three new alpha-amanitin resistance mutations in the gene encoding the largest subunit of mouse RNA polymerase II (RPII215). These mutations are clustered in a region of the largest subunit that is important for transcription elongation. This same domain has been i...

Topics

3T3 Cells
Alleles
Amanitins
Amino Acid Sequence
Animals
Base Sequence
Cell Line
Cloning, Molecular
Drug Resistance
Mice
Mice, Inbred BALB C
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
RNA Polymerase II
Sequence Homology, Amino Acid
Transfection

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