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Article

A preliminary assessment of the toxic and mutagenic potential of steroidal alkaloids in transgenic mice.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association - 1 Mar 1995

Crawford L, Myhr B

Abstract excerpt

Impregnated CD2 transgenic mice, which contain multiple copies of a lambda gt10lacZ construct integrated into the genome of each cell, were given a predetermined estimated maximum tolerated dose of several steroidal alkaloids: Solanum glycoalkaloids from potato, alpha-chaconine and alpha-solanine; aglycones, solanidine and solasodine, and a Veratrum alkaloid, jervine. Observations were made of dams and foetuses...

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Identifiers

PMID: 7896228
DOI: 10.1016/0278-6915(94)00135-b

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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